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Bizengri

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Bizengri

Supplied with complete CDSCO-approved import and customs documentation, including Form 12A & 12B, CDEC, GST Bill of Entry, Commercial Invoice, and Packing List.

Medicine Name: Bizengri
Generic Name (API): Zenocutuzumab-Zbco
Dosage Form & Strength: 375 mg
Route: Intravenous (IV) infusion
Drug Class: Bispecific HER2/HER3-directed antibody

Manufacturer / Innovator:

USA

Regulatory Approval:

  • US FDA
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  • EU-GDP Compliant Warehousing for secure, quality-controlled global distribution.

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  • Temperature-Controlled Logistics for Safe and Timely Delivery

    Temperature-controlled logistics ensuring safe, reliable, and timely medicine delivery.

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What Is Bizengri Used For?

Bizengri (zenocutuzumab-zbco) is a bispecific HER2/HER3-directed antibody that blocks NRG1 from binding to HER3, inhibiting the growth signal driving certain rare cancers. It is indicated for the treatment of adults with:

  • Advanced, unresectable, or metastatic non-small cell lung cancer (NSCLC) harboring an NRG1 gene fusion, with progression on or after prior systemic therapy
  • Advanced, unresectable, or metastatic pancreatic adenocarcinoma harboring an NRG1 gene fusion, with progression on or after prior systemic therapy
  • Advanced, unresectable, or metastatic cholangiocarcinoma (bile duct cancer) harboring an NRG1 gene fusion, with progression on or after prior systemic therapy

NRG1 fusion-positive cancers are rare, and patients are selected for treatment based on confirmed NRG1 fusion testing. It is a prescription oncology medicine and must be administered under the supervision of a qualified oncologist.

Recommended Dosage

  • 750 mg given as an intravenous infusion once every 2 weeks
  • Continued until disease progression or unacceptable toxicity

This information is not a treatment plan. For personalized medical advice, consult your doctor and refer to the full prescribing information.

Bizengri Warnings and Precautions

Boxed Warning — Embryo-Fetal Toxicity: Bizengri can cause fetal harm when used during pregnancy. Effective contraception is required during treatment and for a period after the last dose.

  • Infusion-related reactions: Including hypersensitivity and anaphylaxis, can occur. Patients are monitored during and after infusions.
  • Interstitial lung disease (ILD) / pneumonitis: Patients should be monitored for new or worsening respiratory symptoms.
  • Left ventricular dysfunction: Heart function should be monitored, given the drug's effect on HER2-related signaling pathways.

How to Access Bizengri in India: A 6-Step Process

Step 1 – Search & request your medicine: The patient or treating doctor submits a request with basic details to initiate the access process.

Step 2 – Verification & eligibility review: The team verifies availability and reviews eligibility against regulatory and clinical requirements to ensure a compliant pathway.

Step 3 – Receive quote & delivery timeline: A transparent quotation is shared, covering medicine cost, logistics, and a clear delivery timeline.

Step 4 – Regulatory approval process: Assistance is provided to secure the approvals and documentation required for legal cross-border access.

Step 5 – Temperature-controlled import & handling: The medicine is sourced and transported under strict GDP-compliant, cold-chain conditions to maintain product integrity.

Step 6 – Secure delivery: The medicine is delivered to the patient or treating hospital, with updates provided at each stage.

Note: From request to delivery, every step is designed to ensure your treatment reaches you safely, compliantly, and without unnecessary delays.

Documentation & Availability

What documents are required to import Bizengri to India?

Bizengri (zenocutuzumab-zbco) injection may be imported in the patient's name only, by patients or government hospitals, in line with India's import regulations for unapproved medicines. The following documentation is required:

  • A valid prescription from a qualified doctor
  • The patient's diagnostic reports, including confirmation of NRG1 gene fusion
  • Patient ID proof (issued by the Government of India)

How is the order confirmed?

The order is confirmed only after receipt and verification of a valid prescription from the doctor and, if applicable, an import permit.

Is Bizengri available in India?

Bizengri (zenocutuzumab-zbco injection) is a prescription medicine that legally requires a doctor's prescription to be dispensed. As of current publicly available information, Bizengri is not commercially marketed in India.

However, patients in India can legally access Bizengri through the Named Patient Program (NPP) — an import provision that allows a medicine not yet registered in India to be imported in the name of a specific patient for their personal treatment, under a valid prescription.

Bizengri received US FDA approval for NSCLC and pancreatic adenocarcinoma in December 2024, with a further approval for cholangiocarcinoma in May 2026, ensuring full transparency throughout the process.

Bizengri can be made available to patients, doctors, and hospitals across major cities in India, including Gurgaon, Delhi, Bangalore, Mumbai, Navi Mumbai, Thane, Hyderabad, Mysore, Kerala, Chennai, Coimbatore, Madurai, Kolkata, Ahmedabad, Surat, Vadodara, Pune, Nagpur, Nashik, Jaipur, Udaipur, Lucknow, Kanpur, Gorakhpur, Chandigarh, Mohali, Faridabad, Noida, Ghaziabad, Kochi, Trivandrum, Kozhikode, Thrissur, Kannur, Mangalore, Bhubaneswar, Patna, Ranchi, Raipur, Guwahati, Visakhapatnam, Vijayawada, Goa, Jammu, Srinagar, Dehradun, Bhopal, Indore, Ludhiana, Amritsar, and others — and can facilitate delivery to the patient's treating hospital. Orders are confirmed only after receipt of a valid doctor's prescription and an import permit, where applicable.

Sourcing & Delivery

NamedPatientProgram.com (NPP) can source Bizengri from reliable global channels and facilitate supply to patients, doctors, and hospitals under applicable legal provisions. As a temperature-sensitive biologic, Bizengri requires cold-chain handling throughout transit and must be kept refrigerated between 2°C to 8°C until use. All prescriptions are dispensed and checked by registered pharmacists and dispatched from New Delhi, India, after legal requirements are fulfilled.

For Bizengri cost in India and availability, contact NPP via WhatsApp at +91 98104 69557 | Toll-Free: 1800-1200-365 or email info@namedpatientprogram.com.

Availability of Bizengri Across Major Cities in India

Patients across India can access Bizengri through regulated import pathways, with delivery arranged to the treating hospital based on a valid oncologist's prescription and confirmed NRG1 fusion testing.

Mumbai

A major oncology hub with institutions like Tata Memorial, Mumbai coordinates access to rare fusion-driven cancer therapies like Bizengri for eligible patients.

Delhi

As part of the Delhi NCR region, the city has a strong concentration of cancer centers, making it a key location for accessing targeted NRG1-fusion cancer treatments.

Bangalore

With a growing network of multispecialty oncology hospitals, Bangalore supports access to Bizengri through structured import pathways guided by treating specialists.

Chennai

Home to several reputed cancer treatment centers, Chennai facilitates access to Bizengri for patients with NRG1 fusion-positive tumors.

Hyderabad

A growing hub for oncology care, Hyderabad supports coordinated access to Bizengri for eligible patients under specialist supervision.

Kolkata

Eastern India's leading cancer centers in Kolkata coordinate Bizengri access for patients with rare NRG1-driven cancers.

Pune

With an expanding base of oncology clinics, Pune facilitates timely access to Bizengri under prescription.

Ahmedabad

Gujarat's leading cancer hospitals support regulated access to Bizengri for eligible patients.

Kochi

Kerala's healthcare network, including major cancer centers in Kochi, coordinates access to advanced targeted therapies like Bizengri.

Chandigarh

Serving North India, Chandigarh's oncology centers facilitate access to Bizengri for patients from Punjab, Haryana, and Himachal Pradesh.

Jaipur

Rajasthan's leading hospitals support patient access to Bizengri through the Named Patient Program.

Lucknow

A key referral center for North India, Lucknow facilitates coordinated access to Bizengri under oncologist care.

Bhubaneswar

Odisha's growing oncology sector supports patient access to Bizengri.

Guwahati

As a referral hub for the North-East, Guwahati facilitates access to Bizengri for patients across the region.

Access can also be coordinated for patients in other major Indian cities, subject to a valid prescription and regulatory requirements.

Written By:

Written By: Nitin Goswami, Senior Medical Content Writer
Last Updated: 08 September 2026
Sources: FDA • CDSCO

Medically Reviewed By:

Medically Reviewed By: Shilpi Banerjee, Registered Pharmacist (M.Pharm)
Last Updated: 08 September 2026

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