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Farmorubicin

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Farmorubicin

Supplied with complete CDSCO-approved import and customs documentation, including Form 12A & 12B, CDEC, GST Bill of Entry, Commercial Invoice, and Packing List.

Medicine Name: Farmorubicin
Generic Name (API): Epirubicin
Dosage Form & Strength: 10 mg
Route: Intravenous
Drug Class: Anthracycline topoisomerase II inhibitor (chemotherapy)

Manufacturer / Innovator:

USA

Regulatory Approval:

  • FDA-approved as a component of adjuvant therapy for patients with evidence of axillary node tumor involvement following resection of primary breast cancer (marketed in the US as Ellence; Farmorubicin is the international brand name for the same active ing
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    Temperature-controlled logistics ensuring safe, reliable, and timely medicine delivery.

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Understanding Farmorubicin (Epirubicin) and Its Medical Uses

Farmorubicin (epirubicin) is an anthracycline chemotherapy agent used as part of combination regimens for breast cancer. Farmorubicin is the international brand name; the same active ingredient is marketed in the United States as Ellence.

Approved Indication

Epirubicin is approved as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement following resection of primary breast cancer, typically used in combination with other chemotherapy agents.

How It Works

Epirubicin intercalates into DNA and inhibits topoisomerase II, disrupting DNA replication and transcription in rapidly dividing cancer cells, leading to cell death.

Dosing

The typical starting dose is 100 to 120 mg/m², administered intravenously in repeated 3 to 4 week cycles, either as a single dose on Day 1 or divided across Days 1 and 8 of each cycle, as determined by the treating oncologist based on the overall chemotherapy regimen.

Warnings and Precautions for Farmorubicin

Boxed Warning — Farmorubicin: Farmorubicin can cause myocardial toxicity, including congestive heart failure, which may occur during treatment or months to years after completion, with risk increasing with cumulative dose. It can also cause severe myelosuppression, secondary leukemias, and severe local tissue necrosis if extravasation occurs during administration — it must not be given by the intramuscular or subcutaneous route. Dose reduction is required in patients with hepatic impairment.

Cardiotoxicity

Cardiac function should be assessed before and periodically during treatment, especially as cumulative dose increases. Risk of cardiomyopathy rises from approximately 0.9% at 550 mg/m² to 3.3% at 900 mg/m² cumulative dose.

Myelosuppression

Monitor complete blood counts regularly; dose modification may be needed for severe neutropenia or thrombocytopenia.

Secondary Malignancy

Secondary acute myeloid leukemia has been reported, particularly with higher cumulative doses.

Extravasation

Administer only by experienced personnel via a free-flowing IV line; extravasation can cause severe tissue damage.

Hepatic Impairment

Dose reduction is required in patients with elevated bilirubin or liver enzymes.

  • Cardiac function monitoring is required before and during treatment.
  • Regular blood count monitoring is needed throughout the treatment course.
  • Report any pain, redness, or swelling at the infusion site immediately.

How to Access Farmorubicin in India: A 6-Step Process

Step 1 – Search & request your medicine: The patient or treating doctor submits a request with basic details to initiate the access process.

Step 2 – Verification & eligibility review: The team verifies availability and reviews eligibility against regulatory and clinical requirements to ensure a compliant pathway.

Step 3 – Receive quote & delivery timeline: A transparent quotation is shared, covering medicine cost, logistics, and a clear delivery timeline.

Step 4 – Regulatory approval process: Assistance is provided to secure the approvals and documentation required for legal cross-border access.

Step 5 – Temperature-controlled import & handling: The medicine is sourced and transported under strict GDP-compliant, cold-chain conditions to maintain product integrity.

Step 6 – Secure delivery: The medicine is delivered to the patient or treating hospital, with updates provided at each stage.

Note: From request to delivery, every step is designed to ensure your treatment reaches you safely, compliantly, and without unnecessary delays.

Documentation and Availability of Farmorubicin

Farmorubicin (epirubicin) is manufactured by Pfizer. Farmorubicin is the international brand name for epirubicin; the same active ingredient is marketed in the United States as Ellence.

Documentation Required

Import of Farmorubicin through a Named Patient Program requires a valid prescription from the treating oncologist, breast cancer diagnosis and treatment plan documentation, and supporting clinical documentation as required by Indian regulatory authorities.

Sourcing

NPP sources Farmorubicin directly from Pfizer's authorized supply chain to ensure product authenticity and regulatory compliance.

Sourcing and Delivery of Farmorubicin

Farmorubicin is sourced through verified, GDP-compliant, cold-chain channels from Pfizer's authorized supply chain to ensure authenticity and quality.

Storage Requirements

Farmorubicin should be stored refrigerated at 2°C to 8°C, protected from light. Once the vial is punctured, the solution should be used within 24 hours.

Delivery Process

Once sourced, Farmorubicin is packed and transported under continuous cold-chain conditions to preserve product integrity throughout the import process, with tracking and updates provided at each stage of delivery to the patient or treating hospital in India.

Availability of Farmorubicin Across Major Cities in India

Patients across India can access Farmorubicin through NPP's regulated import pathway, with oncology specialists in major cities supporting the treatment process.

Mumbai

Leading oncology centers in Mumbai support breast cancer treatment coordination for Farmorubicin access.

Delhi

Delhi's major cancer hospitals assist patients with treatment planning and prescription support for Farmorubicin.

Bangalore

Bangalore's oncology network offers access to adjuvant chemotherapy planning for eligible patients.

Chennai

Chennai-based specialists coordinate Farmorubicin access alongside comprehensive breast cancer care.

Hyderabad

Hyderabad's cancer care institutions support patients pursuing Farmorubicin therapy.

Kolkata

Kolkata's oncology centers help coordinate documentation and treatment access for Farmorubicin.

Pune

Pune-based oncologists assist with treatment planning for Farmorubicin.

Ahmedabad

Ahmedabad's specialty hospitals support the import and treatment process for Farmorubicin.

Kochi

Kochi's oncology units assist patients with the documentation needed for Farmorubicin access.

Chandigarh

Chandigarh's cancer care centers support Farmorubicin treatment coordination for patients from North India.

Jaipur

Jaipur's oncology specialists help patients navigate the Farmorubicin access process.

Lucknow

Lucknow-based cancer centers assist patients pursuing Farmorubicin therapy.

Bhubaneswar

Bhubaneswar's oncology institutions support access to Farmorubicin for eligible patients.

Guwahati

Guwahati's specialists help coordinate Farmorubicin access for patients across the Northeast.

Patients in other cities across India can also access Farmorubicin through NPP's nationwide coordination network.

Written By:

Written By: Nitin Goswami, Senior Medical Content Writer
Last Updated: 10 September 2026
Sources: FDA • CDSCO

Medically Reviewed By:

Medically Reviewed By: Shilpi Banerjee, Registered Pharmacist (M.Pharm)
Last Updated: 10 September 2026

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