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Imjudo

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Imjudo

Supplied with complete CDSCO-approved import and customs documentation, including Form 12A & 12B, CDEC, GST Bill of Entry, Commercial Invoice, and Packing List.

Medicine Name: Imjudo
Generic Name (API): Tremelimumab
Dosage Form & Strength: 300 mg
Route: Intravenous
Drug Class: CTLA-4 inhibitor (immune checkpoint inhibitor)

Manufacturer / Innovator:

Germany

Regulatory Approval:

  • FDA-approved (2022) in combination with durvalumab (Imfinzi) for adults with unresectable hepatocellular carcinoma
  • and in combination with durvalumab and platinum-based chemotherapy for adults with metastatic non-small cell lung cancer without sensitizin
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    100% CDSCO-compliant processes ensuring safe, ethical, and responsible medicine access.

  • Medicines sourced from authorized manufacturers with full batch traceability

    Medicines sourced from authorized manufacturers with full batch traceability.

  • EU-GDP Compliant Warehousing for secure, quality-controlled global distribution.

    EU-GDP compliant warehousing for secure, quality-controlled global distribution.

  • Temperature-Controlled Logistics for Safe and Timely Delivery

    Temperature-controlled logistics ensuring safe, reliable, and timely medicine delivery.

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Understanding Imjudo (Tremelimumab-actl) and Its Medical Uses

Imjudo (tremelimumab-actl) is a CTLA-4 immune checkpoint inhibitor used in combination with durvalumab (Imfinzi) to enhance the immune system's ability to recognize and attack cancer cells.

Approved Indications

Imjudo, combined with durvalumab, is FDA-approved for adults with unresectable hepatocellular carcinoma (liver cancer). Combined with durvalumab and platinum-based chemotherapy, it is also approved for adults with metastatic non-small cell lung cancer without sensitizing EGFR mutations or ALK genomic aberrations.

How It Works

Tremelimumab blocks CTLA-4, a checkpoint protein that normally suppresses T-cell activation, allowing the immune system to mount a stronger anti-tumor response, particularly when combined with the PD-L1 inhibitor durvalumab.

Dosing

For hepatocellular carcinoma, the standard dose is 300 mg as a single intravenous dose, combined with durvalumab 1500 mg, followed by durvalumab alone every 4 weeks. For NSCLC, tremelimumab is combined with durvalumab and platinum-based chemotherapy per a defined cycle schedule, as determined by the treating oncologist.

Warnings and Precautions for Imjudo

Imjudo, as an immune checkpoint inhibitor, can cause immune-mediated adverse reactions affecting multiple organ systems.

Immune-Mediated Pneumonitis

Monitor for new or worsening respiratory symptoms; manage with corticosteroids and treatment interruption as needed.

Immune-Mediated Colitis

Monitor for diarrhea or signs of colitis.

Immune-Mediated Hepatitis

Monitor liver function tests before and during treatment.

Immune-Mediated Endocrinopathies

Can affect the thyroid, pituitary, and adrenal glands. Monitor thyroid and other hormone levels periodically.

Immune-Mediated Nephritis and Skin Reactions

Monitor kidney function and for skin changes throughout treatment.

Infusion-Related Reactions

Monitor during and after infusion for hypersensitivity reactions.

Embryo-Fetal Toxicity

Imjudo can cause fetal harm. Effective contraception is required during treatment and for a defined period after the final dose.

  • Regular monitoring for immune-related organ effects is required throughout treatment.
  • Report any new symptoms — breathing changes, diarrhea, rash, or fatigue — to the treating physician promptly.
  • Follow the combination-therapy monitoring schedule established by the treating oncologist.

How to Access Imjudo in India: A 6-Step Process

Step 1 – Search & request your medicine: The patient or treating doctor submits a request with basic details to initiate the access process.

Step 2 – Verification & eligibility review: The team verifies availability and reviews eligibility against regulatory and clinical requirements to ensure a compliant pathway.

Step 3 – Receive quote & delivery timeline: A transparent quotation is shared, covering medicine cost, logistics, and a clear delivery timeline.

Step 4 – Regulatory approval process: Assistance is provided to secure the approvals and documentation required for legal cross-border access.

Step 5 – Temperature-controlled import & handling: The medicine is sourced and transported under strict GDP-compliant, cold-chain conditions to maintain product integrity.

Step 6 – Secure delivery: The medicine is delivered to the patient or treating hospital, with updates provided at each stage.

Note: From request to delivery, every step is designed to ensure your treatment reaches you safely, compliantly, and without unnecessary delays.

Documentation and Availability of Imjudo

Imjudo (tremelimumab-actl) received FDA approval in 2022 and is manufactured by AstraZeneca, used in combination with durvalumab (Imfinzi) for liver cancer and lung cancer.

Documentation Required

Import of Imjudo through a Named Patient Program requires a valid prescription from the treating oncologist, diagnostic confirmation and treatment plan documentation, and supporting clinical documentation as required by Indian regulatory authorities.

Sourcing

NPP sources Imjudo directly from AstraZeneca's authorized supply chain to ensure product authenticity and regulatory compliance.

Sourcing and Delivery of Imjudo

Imjudo is sourced through verified, GDP-compliant, cold-chain channels from AstraZeneca's authorized supply chain to ensure authenticity and quality.

Storage Requirements

Imjudo should be stored refrigerated at 2°C to 8°C. Do not freeze.

Delivery Process

Once sourced, Imjudo is packed and transported under continuous cold-chain conditions to preserve product integrity throughout the import process, with tracking and updates provided at each stage of delivery to the patient or treating hospital in India.

Availability of Imjudo Across Major Cities in India

Patients across India can access Imjudo through NPP's regulated import pathway, with oncology specialists in major cities supporting the treatment process.

Mumbai

Leading oncology centers in Mumbai support liver and lung cancer treatment coordination for Imjudo access.

Delhi

Delhi's major cancer hospitals assist patients with treatment planning and prescription support for Imjudo.

Bangalore

Bangalore's oncology network offers access to combination immunotherapy planning for eligible patients.

Chennai

Chennai-based specialists coordinate Imjudo access alongside comprehensive cancer care.

Hyderabad

Hyderabad's cancer care institutions support patients pursuing Imjudo therapy.

Kolkata

Kolkata's oncology centers help coordinate documentation and treatment access for Imjudo.

Pune

Pune-based oncologists assist with treatment planning for Imjudo.

Ahmedabad

Ahmedabad's specialty hospitals support the import and treatment process for Imjudo.

Kochi

Kochi's oncology units assist patients with the documentation needed for Imjudo access.

Chandigarh

Chandigarh's cancer care centers support Imjudo treatment coordination for patients from North India.

Jaipur

Jaipur's oncology specialists help patients navigate the Imjudo access process.

Lucknow

Lucknow-based cancer centers assist patients pursuing Imjudo therapy.

Bhubaneswar

Bhubaneswar's oncology institutions support access to Imjudo for eligible patients.

Guwahati

Guwahati's specialists help coordinate Imjudo access for patients across the Northeast.

Patients in other cities across India can also access Imjudo through NPP's nationwide coordination network.

Written By:

Written By: Nitin Goswami, Senior Medical Content Writer
Last Updated: 10 September 2026
Sources: FDA • CDSCO

Medically Reviewed By:

Medically Reviewed By: Shilpi Banerjee, Registered Pharmacist (M.Pharm)
Last Updated: 10 September 2026

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